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The Need for Precision Dosing of Biologic Therapeutics

October 13, 2016

Bradley Messmer,PhD

October 2013

Abstract

 

Biologic drugs are among the most powerful and expensive drugs available for many chronic and serious illness. Yet they are often dosed in a "one size fits all" manner, despite extensive literature showing significant variability in pharmacokinetics and exposure in treated populations. An overview of the problem as well as specific case studies will be presented along with a short overview of technologies that can be used for dose monitoring.